Leptin tA PEG
Alternative Names: Not Available
- Sku: PSB-cyt-702-5µg
- Vendor: ProSpec-Tany
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Product Description
Recombinant Human Leptin Triple Antagonist, Pegylated is a bioengineered protein that acts as an antagonist to the hormone leptin, which regulates appetite and energy expenditure. Belonging to the family of pegylated proteins, this therapeutic agent is designed to modulate leptin signaling pathways and potentially aid in the management of obesity and related metabolic disorders. With a weight of approximately [insert weight], this pegylated antagonist exhibits enhanced stability and prolonged circulation in the body, allowing for sustained therapeutic effects. Its mechanism of action offers a promising avenue for research and potential treatment options in the field of obesity management.
Current Lead Time
7-14 Days
Product Specifications
|
Species |
Human |
| Expression System | E. coli |
| Purity | 98% by SDS-PAGE |
|
Activity |
Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher. Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher. |
| Activity Assay | |
| Animal Component Free (ACF) | Yes |
|
Molecular Weight |
N/A |
| Structure | Contact for Details |
|
Endotoxin Concentration |
Not Available |
| Purification Method | Not Available |
|
Form |
Lyophilized |
| Formulation | The protein was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3. |
*For Research Use Only
If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation.
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Leptin tA PEG