LAG-1

Alternative Names: C-C motif chemokine 4-like, CCL4L1, CCL4L2, Lymphocyte activation gene 1 protein, LAG-1, LAG1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like, SCYA4L1, SCYA4L2, AT744.2.

CCL4L1 is a CC chemokine that belongs to the chemokine CC family, similar to CCL4. Both proteins are known to inhibit HIV replication in peripheral blood monocytes expressing CCR5.

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  • Sku: PSB-chm-018-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human LAG-1 (CCL4L1) is a member of the chemokine family, specifically belonging to the CC chemokine subfamily. With a molecular weight of approximately 8.4 kDa, this protein plays a role in immune response and inflammation by regulating the migration and activation of various immune cells. Recombinant Human LAG-1 (CCL4L1) is commonly used in research settings to study the mechanisms of chemotaxis and immune cell recruitment.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation LAG-1 was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN.

Storage Instruction

Lyophilized LAG-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL4L1 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized LAG-1 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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LAG-1

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