k9IL8

Alternative Names: Interleukin-8, IL-8, C-X-C motif chemokine 8, IL8, CXCL8.

Interleukin-8 (IL-8) is a chemokine produced by various cell types, including macrophages and endothelial cells. It is stored in Weibel-Palade bodies in endothelial cells. Macrophages release IL-8 as a signal to attract neutrophils to sites of inflammation, playing a key role in immune response.

  •
  • Sku: PSB-chm-009-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Canine Interleukin-8 is a chemokine protein that plays a key role in the immune response of dogs by attracting and activating neutrophils to sites of inflammation. Belonging to the CXC chemokine family, this protein is involved in the regulation of neutrophil migration and activation. With a molecular weight of approximately 8.3 kDa, Recombinant Canine Interleukin-8 is a crucial mediator in the inflammatory process in canines.

Current Lead Time

7-14 Days

Product Specifications

Species
 Dog
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.15-0.75 ng/ml. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.15-0.75 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AVLSRVSSEL RCQCIKTHST PFHPKYIKEL RVIDSGPHCE NSEIIVKLFN GNEVCLDPKE KWVQKVVQIF LKKAEKQDP.

Storage Instruction

Lyophilized IL-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized ;IL-8 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

k9IL8
SUBHEADING

Recently viewed products