k9IL21

Alternative Names: "

Interleukin-21.

, Interleukin-21."

Interleukin-21 isoform 1 (IL21) is a T helper cytokine involved in regulating immune responses, haematopoiesis, and cell-mediated responses. It plays a significant role in haematopoiesis and the regulation of immune responses, specifically impacting lymphocyte development. Additionally, IL21 is produced when T cells are activated and is crucial in maintaining the persistence of viral infections.

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  • Sku: PSB-cyt-1181-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Canine Interleukin-21 (IL-21) is a genetically engineered protein that belongs to the cytokine family. IL-21 plays a crucial role in regulating immune responses and inflammation in canines. With a molecular weight of approximately X kDa, this protein acts as a signaling molecule, binding to specific receptors on immune cells and activating downstream signaling pathways. Its precise role in canine physiology and potential therapeutic applications are areas of ongoing scientific research.

Current Lead Time

7-14 Days

Product Specifications

Species
Canine
Expression System E. coli
Purity 95.0 by SDS-PAGE
Activity
The activity is determined by the IFN-g ELISA in a using NK-92 human natural killer cells. The ED50 range ≤ 2ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation IL21 protein solution (0.5mg/ml) containing Phosphate-Buffered Saline (pH7.4).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MHKSSFQEQD LLLIRMRQLI DIVDQLKNYV NDLDPESLPA PEDVKRHCER SAFSCFQKVQ LKAANTGGNE QIINVLTKQL KRKLPPTNAG RRQKHRPACP SCDSYEKAPP KEFLERLKSL IQKMIHQHLS

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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k9IL21

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