Inhibin a

Alternative Names: Not Available

Inhibins are dimeric peptide hormones produced by ovarian granulose cells and Sertoli cells in males. There are two isoforms of inhibins, A and B, with the same alpha subunit but different beta subunits. Inhibin A is composed of alpha and beta A subunits, while inhibin B is made up of alpha and beta B subunits. Inhibins are believed to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland and are thought to be involved in regulating gametogenesis, as well as embryonic and fetal development.

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  • Sku: PSB-hor-303-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Inhibin-Alpha is a protein belonging to the TGF-beta superfamily, known for its role in regulating follicle-stimulating hormone secretion in the pituitary gland. With a molecular weight of approximately 32 kDa, this protein plays a crucial role in the inhibition of activin-induced FSH secretion, making it a valuable tool in reproductive research and therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation Inhibin-A alpha chain is supplied in20mM Trisand 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Alpha chain:STPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP PNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCACI.Beta Chain:GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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Inhibin a

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