IMPDH1

Alternative Names: EC 1.1.1.205, IMPDH 1, IMPD 1, IMPDH-I, IMP (inosine monophosphate) dehydrogenase 1, LCA11, RP10, SwSS2608, DKFZp781N0678.

Recombinant Human IMP Dehydrogenase 1 is an enzyme that plays a key role in the de novo purine biosynthesis pathway. Belonging to the IMPDH family, this enzyme is responsible for catalyzing the conversion of inosine monophosphate (IMP) to xanthosine monophosphate (XMP) using NAD+ as a cofactor. With a molecular weight of approximately 55 kDa, Recombinant Human IMP Dehydrogenase 1 is a crucial enzyme in the regulation of cellular nucleotide pools.

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  • Sku: PSB-enz-525-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human IMP Dehydrogenase 1 is an enzyme that plays a key role in the de novo purine biosynthesis pathway. Belonging to the IMPDH family, this enzyme is responsible for catalyzing the conversion of inosine monophosphate (IMP) to xanthosine monophosphate (XMP) using NAD+ as a cofactor. With a molecular weight of approximately 55 kDa, Recombinant Human IMP Dehydrogenase 1 is a crucial enzyme in the regulation of cellular nucleotide pools.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homotetramer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation IMPDH1 Human solution containing 20mM Tris-HCl pH-8, 1mM DTT & 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MADYLISGGT GYVPEDGLTA QQLFASADGL TYNDFLILPG FIDFIADEVD LTSALTRKIT LKTPLISSPM DTVTEADMAI AMALMGGIGF IHHNCTPEFQ ANEVRKVKKF EQGFITDPVV LSPSHTVGDV LEAKMRHGFS GIPITETGTM GSKLVGIVTS RDIDFLAEKD HTTLLSEVMT PRIELVVAPA GVTLKEANEI LQRSKKGKLP IVNDCDELVA IIARTDLKKN RDYPLASKDS QKQLLCGAAV GTREDDKYRL DLLTQAGVDV IVLDSSQGNS VYQIAMVHYI KQKYPHLQVI GGNVVTAAQA KNLIDAGVDG LRVGMGCGSI CITQEVMACG RPQGTAVYKV AEYARRFGVP IIADGGIQTV GHVVKALALG ASTVMMGSLL AATTEAPGEY FFSDGVRLKK YRGMGSLDAM EKSSSSQKRY FSEGDKVKIA QGVSGSIQDK GSIQKFVPYL IAGIQHGCQD IGARSLSVLR SMMYSGELKF EKRTMSAQIE GGVHGLHSYE KRLY.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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IMPDH1

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