IL 8 Pichia

Alternative Names: Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctakin, K60, NAF, LECT, LUCT, 3-10C, LYNAP, SCYB8, TSG-1, AMCF-I, b-ENAP, IL-8, CXCL8.

Interleukin-8 (IL-8) is a chemokine produced by various cell types such as macrophages, epithelial cells, and endothelial cells. Endothelial cells store IL-8 in Weibel-Palade bodies. When an antigen is encountered, macrophages phagocytose it and release chemokines like IL-8 to attract immune cells to the site of inflammation, specifically neutrophils. IL-8 acts as a Neutrophil Chemotactic Factor.

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  • Sku: PSB-chm-349-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Interleukin-8 (1-77) (CXCL8) Pichia is a protein belonging to the chemokine family. With a molecular weight of approximately 8.5 kDa, this protein plays a key role in the immune response by promoting the migration and activation of neutrophils at sites of inflammation. Produced in Pichia pastoris yeast cells, Recombinant Human Interleukin-8 (1-77) (CXCL8) Pichia is widely used in research and pharmaceutical applications for studying inflammatory processes and developing therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Pichia Pastoris
Purity 98% by SDS-PAGE
Activity
Chemotactic activity was reached at 25ng/ml on human neutrophils.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a concentrated (1mg/ml) solution in water containing 20mM sodium phosphate buffer pH-8.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

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Storage Instruction

Lyophilized Interleukin-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Interleukin 8 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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IL 8 Pichia

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