IL 8 (1-77)

Alternative Names: Neutrophil-activating protein 1, NAP-1, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Protein 3-10C, T-cell chemotactic factor, IL-8, CXCL8, Emoctakin, K60, NAF, LECT, LUCT, 3-10C, LYNAP, SCYB8, TSG-1, AMCF-I, b-ENAP.

Interleukin-8 (IL-8) is a type of chemokine that is produced by various cell types, including macrophages, epithelial cells, and endothelial cells. Endothelial cells store IL-8 in their Weibel-Palade bodies. Macrophages are the first cells to encounter antigens, and upon phagocytosis, they release chemokines like IL-8 to attract other immune cells to the site of inflammation. IL-8 specifically attracts neutrophils and is therefore referred to as Neutrophil Chemotactic Factor.

  •
  • Sku: PSB-chm-327-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Interleukin-8 (1-77) (CXCL8) is a chemokine belonging to the CXC subfamily. With a molecular weight of approximately 8.3 kDa, this protein plays a key role in the recruitment and activation of neutrophils at sites of inflammation. CXCL8 is involved in various inflammatory processes and immune responses, making it a valuable tool for research in immunology and related fields.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25-150 ng/ml. Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25-150 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS.

Storage Instruction

Lyophilized Interleukin-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Interleukin 8 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

IL 8 (1-77)
SUBHEADING

Recently viewed products