I TAC, His

Alternative Names: Small inducible cytokine B11, SCYB11, CXCL11, chemokine (C-X-C motif) ligand 11, Interferon-inducible T-cell alpha chemoattractant, I-TAC, SCYB9B, Interferon-gamma-inducible protein 9, IP-9, IP9, H174, MGC102770, Beta-R1, b-R1.

CXCL11 is a small cytokine in the CXC chemokine family, also known as I-TAC and IP-9. It is highly expressed in blood leukocytes, pancreas, and liver and has moderate levels in thymus, spleen, and lung. It has lower expression in small intestine, placenta, and prostate. CXCL11 gene expression is strongly induced by IFN-g and IFN-b, and weakly induced by IFN-a. It interacts with the chemokine receptor CXCR3 with high affinity, compared to CXCL9 and CXCL10. CXCL11 attracts activated T cells and is located on human chromosome 4 with other CXC chemokines.

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  • Sku: PSB-chm-232-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human I-TAC (CXCL11), His Tag is a protein belonging to the CXC chemokine family. This protein plays a role in immune response and inflammation by attracting immune cells to sites of infection or injury. With a molecular weight of approximately 9.5 kDa, Recombinant Human I-TAC (CXCL11) is commonly used in research settings to study chemotaxis and immune cell recruitment mechanisms. This protein can be utilized in various assays and experiments to investigate the function and signaling pathways of chemokines in the immune system.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
10.6 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The I-TAC solution (1mg/ml) contains 10mM sodium citrate(pH 3.5), 20% glycerol and 2mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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I TAC, His

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