I 309

Alternative Names: Small inducible cytokine A1, CCL1, chemokine (C-C motif) ligand 1, T lymphocyte-secreted protein I-309, P500, SISe, TCA3, I-309, SCYA1.

CCL1 is a small glycoprotein secreted by activated T cells that belongs to the chemokine family of inflammatory cytokines. It interacts with the CCR8 receptor to attract monocytes, NK cells, immature B cells, and dendritic cells. CCL1 is located on human chromosome 17 within a cluster of CC chemokines.

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  • Sku: PSB-chm-312-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human I-309 (CCL1) is a chemokine belonging to the CC family. It plays a role in the regulation of immune responses and inflammation by attracting immune cells to sites of infection or injury. With a molecular weight of approximately 8.4 kDa, Recombinant Human I-309 is commonly used in research settings to study chemotaxis and immune cell migration. Its ability to modulate the immune system makes it a valuable tool for investigating inflammatory diseases and potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 99.0% by SDS-PAGE
Activity
 The Biological activity is calculated by its ability to chemoattract human T cells at 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg. The Biological activity is calculated by its ability to chemoattract human T cells at 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The CCL1 protein was lyophilized with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Lys-Ser-Met-Gln.

Storage Instruction

Lyophilized I-309 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized I-309 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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I 309
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