HTATIP2

Alternative Names: HIV-1 TAT-interactive protein 2, FLJ26963, TIP30, CC3, SDR44U1, HTATIP2, EC=1.1.1.-

HTATIP2, a member of the SDR family, functions as a tumor suppressor by inhibiting metabolism, angiogenesis, and promoting apoptosis genes like Bad and Siva. It works in conjunction with the activation domain of HIV-1 TAT to enhance transcription by phosphorylating RNA polymerase II. Deficiencies in HTATIP2 are associated with liver cancer and tumor cells resistant to apoptosis, suggesting its potential as a therapeutic target for treating cancer.

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  • Sku: PSB-enz-546-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human HIV-1 Tat Interactive Protein 2 is a member of the Tat-interacting protein family, which plays a role in the regulation of HIV-1 gene expression. This protein has a molecular weight of approximately 32 kDa and is involved in mediating interactions between the HIV-1 Tat protein and cellular factors. Recombinant Human HIV-1 Tat Interactive Protein 2 is commonly used in research settings to study the molecular mechanisms underlying HIV-1 replication and pathogenesis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation HTATIP2 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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HTATIP2

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