HMOX2

Alternative Names: EC 1.14.99.3, HO2, HO-2, Heme oxygenase 2, HMOX2

HMOX2 is an enzyme that plays a critical role in breaking down heme to form biliverdin, which is then converted to bilirubin by biliverdin reductase. HMOX2 is most active in the spleen, where it helps destroy old red blood cells. It also produces carbon monoxide in the brain, acting as a neurotransmitter. Additionally, HMOX2 is essential for heme breakdown and helps cells respond to oxidative stress.

Skip to product information
  • Sku: PSB-enz-478-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Heme Oxygenase 2 is an enzyme that belongs to the heme oxygenase family, specifically the HO-2 isoform. This enzyme is responsible for catalyzing the degradation of heme into biliverdin, carbon monoxide, and free iron. Recombinant Human Heme Oxygenase 2 has a molecular weight of approximately 32 kDa and plays a key role in the regulation of cellular heme levels. Its enzymatic activity is crucial for maintaining cellular homeostasis and responding to oxidative stress.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation HMOX2 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

HMOX2

SUBHEADING

Recently viewed products