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HCC 1 (66 a.a.)

Alternative Names: Small inducible cytokine A14, SCYA14, CCL14, chemokine CC-1/CC-3, CC-1, CC-3, HCC-1, HCC-3, HCC-1(1-74), NCC-2, chemokine (C-C motif) ligand 14, CKb1, MCIF, SY14, SCYL2.

CCL14, also known as HCC-1, is a small cytokine within the CC chemokine family. It is produced as a protein precursor and processed to create a mature active protein with 74 amino acids. CCL14 is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is found in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL13 activates monocytes but does not induce their chemotaxis. The human CCL13 gene is located on chromosome 17 with other CC chemokines.

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  • Sku: PSB-chm-006-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human HCC-1 (CCL14) (66 a.a.) is a member of the CC chemokine family, known for their role in immune response regulation. This protein has a molecular weight of 7.6 kDa and is involved in the recruitment and activation of immune cells. Recombinant Human HCC-1 (CCL14) (66 a.a.) is commonly used in research settings to study inflammatory processes and immune system functioning.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 The Biological activity is determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml. The Biological activity is determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The CCL14 protein was lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4 and 5% trehalose.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN.

Storage Instruction

Lyophilized HCC1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL14 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized HCC-1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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HCC 1 (66 a.a.)
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