HbA1c

Alternative Names: Not Available

The HbA1c is a measure of the average blood glucose concentration over a 3-month period. Glucose in the blood can bind to hemoglobin in red blood cells, a process known as glycosylation. This attachment remains for the lifespan of the red blood cell, which is approximately 120 days. Higher blood sugar levels result in more sugar attaching to red blood cells. HbA1c is produced through the non-enzymatic exposure of hemoglobin to increased plasma glucose levels. It is used to monitor nephropathy and retinopathy in diabetes mellitus.

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  • Sku: PSB-pro-299-100µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Human Hemoglobin A1c is a glycosylated form of hemoglobin, belonging to the globin protein family. With a molecular weight of approximately 64,500 Daltons, it plays a significant role in monitoring long-term glycemic control in individuals with diabetes. Hemoglobin A1c is formed when glucose molecules attach to the beta chains of hemoglobin in a non-enzymatic process known as glycation. This stable glycated hemoglobin remains in circulation for around 120 days, providing a reliable indicator of average blood glucose levels over the preceding two to three months. The measurement of Hemoglobin A1c is widely used in clinical settings to assess diabetes management and guide treatment decisions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Human Erythrocytes
Purity 96.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The HbA1c is supplied in a proprietary buffer formulation having pH-8.0. The HbA1c was dispensed on the basis of HbA1c not total hemoglobin.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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HbA1c

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