GZMH

Alternative Names: Granzyme H, Granzyme H (Cathepsin G-Like 2, Protein H-CCPX), CGL-2, CGL2, Cathepsin G-Like 2, CTSGL2, EC 3.4.21, EC 3.4.21.79, EC 3.4.21, CSP-C, Cytotoxic Serine Protease C, CCP-X, Cytotoxic T-Lymphocyte Proteinase, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1, CTLA1, Cytotoxin Serine Protease-C, Cytotoxic T-Lymphocyte Proteinase, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1, GZMH.

Recombinant Human Granzyme-H is a serine protease that belongs to the granzyme family. It plays a role in inducing apoptosis in target cells by cleaving specific substrates. With a molecular weight of approximately 29 kDa, Recombinant Human Granzyme-H is commonly used in research and therapeutic applications for its ability to trigger cell death in a variety of cell types.

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  • Sku: PSB-enz-896-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Granzyme-H is a serine protease that belongs to the granzyme family. It plays a role in inducing apoptosis in target cells by cleaving specific substrates. With a molecular weight of approximately 29 kDa, Recombinant Human Granzyme-H is commonly used in research and therapeutic applications for its ability to trigger cell death in a variety of cell types.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
27.5 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation GZMH protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRL

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GZMH

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