GSTO1 Mutant

Alternative Names: Glutathione S-transferase omega-1, GSTO1, GSTO 1-1, GSTTLP28, P28, DKFZp686H13163.

GSTO1 is a member of the GSTTL protein family, expressed in various human tissues. It has thiol transferase and dehydroascorbate reductase activities, as well as catalyzing the reduction of monomethylarsonate in the pathway of arsenic metabolism. GSTO1 contributes to protection against oxidative stress, associated with conditions like Alzheimer's disease and stroke. Its levels are decreased in patients with chronic obstructive pulmonary disease. In mice, GSTO1 plays a role in maintaining cellular redox balance as a small stress response protein.

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  • Sku: PSB-enz-435-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Glutathione S-Transferase Omega 1 Mutant is a variant of the GSTO1 gene, a member of the glutathione S-transferase family involved in cellular detoxification processes. This mutant protein has a molecular weight of approximately 28 kDa and exhibits altered enzymatic activity compared to the wild-type GSTO1. Its unique properties make it a valuable tool for studying the role of GSTO1 in oxidative stress and disease pathogenesis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation GSTO1 protein is supplied in 1x PBS and 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GSTO1 Mutant

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