GSTO1

Alternative Names: Glutathione S-transferase omega-1, GSTO1, GSTO 1-1, GSTTLP28, P28, DKFZp686H13163.

GSTO1 is a member of the GSTTL protein family and is found in various human tissues. It has thiol transferase and dehydroascorbate reductase activities, as well as the ability to reduce monomethylarsonate in arsenic biotransformation. GSTO1 also plays a role in protecting against oxidative stress, which is linked to diseases such as Alzheimer's, vascular dementia, and stroke. In chronic obstructive pulmonary disease patients, levels of GSTO1 are lower, particularly in alveolar macrophages and airway secretions. In mice, GSTO1 serves as a small stress response protein involved in maintaining cellular redox balance.

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  • Sku: PSB-enz-434-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Glutathione S-Transferase Omega 1 is a protein belonging to the glutathione S-transferase family, which plays a role in the detoxification of electrophilic compounds. With a molecular weight of approximately 25 kDa, this enzyme is involved in the conjugation of reduced glutathione to a variety of substrates, aiding in the removal of potentially harmful molecules from the body. Recombinant Human Glutathione S-Transferase Omega 1 is commonly used in research and biotechnological applications due to its ability to efficiently catalyze glutathione-dependent reactions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation GSTO1 protein is supplied in 20 mM Tris pH 8.0 and 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GSTO1

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