GSTM1, Sf9

Alternative Names: GST 1-1, GST class-mu 1, GST1, GSTM1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, Glutathione S-transferase Mu 1, Glutathione S-transferase GT8.7, pmGT10, GTH4, GTM1, MGC26563.

Two supergene families encode cytosolic and membrane-bound types of GST. The eight classes of soluble cytoplasmic mammalian GST are alpha, kappa, mu, omega, pi, sigma, theta, and zeta. The mu class of enzymes plays a key role in detoxifying electrophilic compounds by conjugating them with glutathione. These enzymes are encoded by genes located together on chromosome 1p13.3 and exhibit high levels of genetic variability. Variations in these genes can impact an individual's resistance to carcinogens and toxins, as well as alter the toxicity and effectiveness of certain drugs. Null mutations in the mu class gene have been associated with an increased risk of developing various cancers.

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  • Sku: PSB-enz-1092-2µg
  • Vendor: ProSpec-Tany
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Product Details

Product Description

Recombinant Human Glutathione S-Transferase M1, Sf9 is a member of the glutathione S-transferase family, a group of enzymes involved in detoxification processes within cells. This particular enzyme has a molecular weight of approximately 26 kDa. Recombinant Human Glutathione S-Transferase M1, Sf9 is commonly used in research and biotechnology applications due to its ability to catalyze the conjugation of reduced glutathione to a wide range of hydrophobic electrophiles.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Insect cells
Purity 90.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 26.8 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation GSTM1 protein solution (0.5mg/ml) contains 40% glycerol, 0.2M NaCl, 2mM DTT and 0.1mM PMSF.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPMPMILGY WDIRGLAHAI RLLLEYTDSS YEEKKYTMGD APDYDRSQWL NEKFKLGLDF PNLPYLIDGA HKITQSNAIL CYIARKHNLC GETEEEKIRV DILENQTMDN HMQLGMICYN PEFEKLKPKY LEELPEKLKL YSEFLGKRPW FAGNKITFVD FLVYDVLDLH RIFEPKCLDA FPNLKDFISR FEGLEKISAY MKSSRFLPRP VFSKMAVWGN KHHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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GSTM1, Sf9
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