GSTA4

Alternative Names: Glutathione S-transferase A4, Glutathione S-transferase A4-4, GST class-alpha member 4, GSTA4, GSTA4-4.

GSTA4, a member of the GST superfamily, plays a significant role in defending cells against harmful electrophilic compounds. It is particularly effective at catalyzing the conjugate addition of reduced glutathione to 4-hydroxynonenal, a biomarker for oxidative damage. GSTA4 is highly expressed in the brain, placenta, and skeletal muscle, with lower levels in the lung and liver.

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  • Sku: PSB-enz-600-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Glutathione S-Transferase Alpha 4 is a protein belonging to the glutathione S-transferase family, which plays a role in detoxification by catalyzing the conjugation of reduced glutathione to a wide variety of exogenous and endogenous hydrophobic electrophiles. This protein has a molecular weight of approximately 25 kDa and is commonly used in research and drug development for its ability to bind to and metabolize toxic compounds.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
28.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The GSTA4 solution (1mg/ml) contains 20mM Tris-HCl buffer, pH8.0, 20% glycerol, 2mM DTT and 100mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAARPK LHYPNGRGRM ESVRWVLAAA GVEFDEEFLE TKEQLYKLQD GNHLLFQQVP MVEIDGMKLV QTRSILHYIA DKHNLFGKNL KERTLIDMYV EGTLDLLELL IMHPFLKPDD QQKEVVNMAQ KAIIRYFPVF EKILRGHGQS FLVGNQLSLADVILLQTILA LEEKIPNILS AFPFLQEYTV KLSNIPTIKR FLEPGSKKKP PPDEIYVRTV YNIFRP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GSTA4

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