GNPNAT1

Alternative Names: Gpnat1, Glucosamine-Phosphate N-Acetyltransferase 1, GNPNAT, GNA1, EC 2.3.1.4, FLJ10607, Phosphoglucosamine acetylase, Phosphoglucosamine transacetylase, Glucosamine 6-Phosphate N-Acetyltransferase.

GNPNAT1, a member of the GNA1 subfamily of acetyltransferase proteins, plays a crucial role in the biosynthesis of UDPGlcNAc. It is localized in the Golgi apparatus and endosome where it catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P. This enzyme is essential for the formation of UDP-GlcNAc6P.

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  • Sku: PSB-enz-037-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Glucosamine-Phosphate N-Acetyltransferase 1 is an enzyme that belongs to the N-Acetyltransferase family. It plays a role in the biosynthesis of N-acetylglucosamine-6-phosphate, a key metabolite in the hexosamine biosynthetic pathway. This enzyme has a molecular weight of approximately 34 kDa and is involved in the acetylation of glucosamine-6-phosphate, an important step in the production of UDP-N-acetylglucosamine.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The GNPNAT1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMKPDETP MFDPSLLKEV DWSQNTATFS PAISPTHPGE GLVLRPLCTA DLNRGFFKVL GQLTETGVVS PEQFMKSFEH MKKSGDYYVT VVEDVTLGQI VATATLIIEH KFIHSCAKRG RVEDVVVSDE CRGKQLGKLL LSTLTLLSKK LNCYKITLEC LPQNVGFYKK FGYTVSEENY MCRRFLK

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GNPNAT1

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