GLP1R

Alternative Names: GLP1, GLP2, GRPP

The GLP1R is a receptor protein found on brain neurons and beta cells of the pancreas, encoded by the GLP1R gene on chromosome 6. When activated, GLP1R triggers a signaling cascade leading to increased cAMP levels. This receptor plays a role in regulating blood sugar levels by enhancing insulin secretion. GLP1R belongs to the glucagon receptor family of G protein-coupled receptors and consists of two domains: a transmembrane domain that binds the N-terminal region of GLP-1, and an extracellular domain that binds the C-terminal helix of GLP-1. The polar residues in the TMD domain control biased signaling, while helical boundaries and the extracellular surface trigger biased agonism.

  •
  • Sku: PSB-hor-027-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Glucagon Like Peptide 1 Receptor is a protein that belongs to the G protein-coupled receptor family. It plays a key role in regulating glucose metabolism and insulin secretion. This receptor has a molecular weight of approximately 55 kDa. Its activation by glucagon-like peptide 1 leads to increased insulin release and improved glycemic control in the body.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90.0 by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation GLP1R filtered (0.4 µm) and lyophilized from 0.5mg/ml in 50mM Acetate Buffer, pH 4.0.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MKHHHHHHAS RPQGATVSLW ETVQKWREYR RQCQRSLTED PPPATDLFCN RTFDEYACWP DGEPGSFVNV SCPWYLPWAS SVPQGHVYRF CTAEGLWLQK DNSSLPWRDL SECEESKRGE RSSPEEQLLF LY

Storage Instruction

Store lyophilized protein at -20° C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4° C for a limited period of time; it does not show any change after two weeks at 4° C.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Hepatocyte Growth Factor in 100mM Acetate buffer to a working concentration approximately 0.5mg/ml. Further dilutions should be made using buffer containing protein.

References

Not Available
View full details

GLP1R
SUBHEADING

Recently viewed products