GLP1

Alternative Names: Incretin hormone, GLP1, Glucagon Like Peptide-1

GLP-1 is a hormone produced by intestinal L cells from the proglucagon gene. The active forms of GLP-1 are GLP-1-(7-37) and GLP-1-(7-36)NH2. Secretion of GLP-1 is stimulated by nutrients in the small intestine, such as carbohydrates, proteins, and lipids. Once released into the bloodstream, GLP-1 has a short half-life due to degradation by dipeptidyl peptidase-4. GLP-1 is being studied for its potential in treating diabetes mellitus because of its ability to increase insulin secretion, decrease glucagon secretion, promote beta cell growth, inhibit acid secretion and gastric emptying, and reduce food intake.

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  • Sku: PSB-hor-284-1mg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Human Glucagon Like Peptide-1 (7-36) is a peptide hormone belonging to the glucagon family. It plays a role in regulating blood sugar levels by stimulating insulin secretion and inhibiting glucagon release. With a molecular weight of approximately 3297.4 g/mol, this hormone is involved in the control of glucose metabolism and satiety. Its physiological functions make it a target for therapeutic interventions in the management of diabetes and obesity.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Contact for Details
Purity 96.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The GLP-1 peptide was lyophilized with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.

Storage Instruction

Lyophilized Glucagon Like Peptide-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GLP-1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Glucagon Like Peptide-1 in sterile H2O at 0.5mg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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GLP1

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