GLC8

Alternative Names: GLC8, Protein GLC8, YM9924.03C, YMR311C

GLC8, a regulatory subunit of protein phosphatase 1 (Glc7p), is involved in glycogen metabolism and chromosome segregation. It modulates the activity of Glc7p by inducing conformational changes. GLC8 is analogous to the mammalian protein phosphatase inhibitor 2. While GLC8 typically activates GLC7, overexpression of GLC8 inhibits the function of Glc7p. Activation of GLC8 occurs when it is phosphorylated by the Pho85p complex, which is associated with four cyclins (Pcl6p, Pcl7p, Pcl8p, or Pcl10p).

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  • Sku: PSB-pro-540-10µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Yeast GLC8 is a protein that belongs to the family of yeast protein phosphatases. With a molecular weight of approximately X kDa, it plays a significant role in regulating various cellular processes through its enzymatic activity. This protein has been extensively studied due to its involvement in signal transduction pathways and its potential as a therapeutic target for certain diseases. The recombinant form of Yeast GLC8 offers a valuable tool for researchers to investigate its structure, function, and interactions with other cellular components.

Current Lead Time

7-14 Days

Product Specifications

Species
Yeast
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Activity Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The protein solution (1mg/ml) contains 20mM Tris-HCl pH-8, 1mM DTT, and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGGI LKNPLALSPE QLAQQDPETL EEFRRQVYEN TQKNAKLTSH KRNIPGLDNT KEEGEIIGTS STFLPKDTLS LKHEQDMLAK MTPEERVQWN QRNLAENEIT KKQFQDIHID EPKTPYQGAV DPHGEYYRVD DDEDEDNSDK KPCQVANDDI DDLSLGEPEF EIKENKQPDF ETNDENDEDS PEARHKKFEE MRKKHYDVRA IFNKKSREAL KDEDEDEDDS TTKEP.

Storage Instruction

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GLC8

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