GHRL

Alternative Names: Ghrelin, Obestatin, Growth hormone-releasing peptide, GHRP, Growth hormone secretagogue, Appetite-regulating hormone precursor, Motilin-related peptide, M46 protein.

Obestatin, a hormone produced in the stomach and small intestine of mammals, including humans, reduces appetite in mice and is expected to have a similar effect in humans. It is a peptide hormone encoded by the same gene as ghrelin, another peptide hormone that increases appetite. The gene produces a protein that breaks down into two peptides, ghrelin and obestatin. Ghrelin acts as a ligand for the growth hormone secretagogue receptor, regulating growth hormone release. Obestatin, on the other hand, acts as a ligand for the orphan G protein-coupled receptor GPR39, contributing to feelings of satiety and reduced food intake.

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  • Sku: PSB-hor-294-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Ghrelin is a peptide hormone belonging to the ghrelin family, known for its role in regulating appetite and energy balance. With a molecular weight of approximately 3.3 kDa, this hormone is produced primarily in the stomach and acts on the hypothalamus to stimulate hunger and promote food intake. Recombinant Human Ghrelin is commonly used in research settings to study its effects on metabolism and potential therapeutic applications in conditions such as obesity and eating disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The Ghrelin protein solution contains 20mM Tris-HCl, pH-8 & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSSFLSPEH QRVQQRKESK KPPAKLQPRA LAGWLRPEDG GQAEGAEDEM EVRFNAPFDV GIKLSGVQYQ QHSQALGKFL QDILWEEAKE APADK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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GHRL

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