FGL1

Alternative Names: Fibrinogen-like protein 1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1, FGL1, HFREP1.

FGL1 is a member of the fibrinogen family and shares similarities with the carboxy terminus of the fibrinogen beta- and gamma- subunits. However, FGL1 lacks certain elements that are essential for the formation of fibrin clots, such as the platelet-binding site, cross-linking region, and a thrombin-sensitive site. It is worth noting that fibrinogen has been found to play a role in the development of hepatocellular carcinomas.

  •
  • Sku: PSB-pro-2580-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Fibrinogen Like 1 (FGL1) is a protein belonging to the fibrinogen-like domain family. With a molecular weight of approximately X kDa, FGL1 plays a significant role in various biological processes. This protein exhibits potential therapeutic applications due to its involvement in liver regeneration, immune modulation, and tumor growth regulation. Understanding the functions and mechanisms of FGL1 can provide valuable insights into developing targeted therapies for liver diseases and cancer.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 35.3 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation FGL1 filtered (0.4 µm) and lyophilized from 0.5mg/ml in in 100 mM carbonate buffer, pH 9.2.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MKHHHHHHAS LEDCAQEQMR LRAQVRLLET RVKQQQVKIK QLLQENEVQF LDKGDENTVI DLGSKRQYAD CSEIFNDGYK LSGFYKIKPL QSPAEFSVYC DMSDGGGWTV IQRRSDGSEN FNRGWKDYEN GFGNFVQKHG EYWLGNKNLH FLTTQEDYTL KIDLADFEKN SRYAQYKNFK VGDEKNFYEL NIGEYSGTAG DSLAGNFHPE VQWWASHQRM KFSTWDRDHD NYEGNCAEED QSGWWFNRCH SANLNGVYYS GPYTAKTDNG IVWYTWHGWW YSLKSVVMKI RPNDFIPNVI.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. FGL1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

References

Not Available
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FGL1
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