FGF19, His

Alternative Names: FGF-19, Fibroblast growth factor 19

FGFs are small secreted peptides that stimulate fibroblast proliferation via specific receptors. There are at least five subfamilies of high-affinity FGF receptors (FGFRs) - FGFR-1, -2, -3, -4, and -5 - with various roles in cellular modulation. Evidence suggests that FGFRs are involved in regulating glucose and lipid homeostasis, with implications for diabetes and pancreatic development. FGF-19 has been linked to resistance to obesity and insulin desensitization, while FGF-21 activates glucose uptake in adipocytes and has beneficial effects on blood glucose and lipid levels in diabetic rodents. Overall, FGFs play a crucial role in controlling energy expenditure and metabolic functions.

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  • Sku: PSB-cyt-279-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Fibroblast Growth Factor-19 His Tag is a protein belonging to the fibroblast growth factor (FGF) family, which plays a key role in cell growth, development, and repair. This particular protein has a molecular weight of approximately 24 kDa and contains a histidine (His) tag for easy purification and detection in laboratory settings. Recombinant Human Fibroblast Growth Factor-19 His Tag is commonly used in research and biotechnology applications to study its effects on cell proliferation and differentiation.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Filtered (0.4µm) and lyophilized from 0.5mg/ml in 20mM TRIS, 20mM NaCl, pH 7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASLAFSDA GPHVHYGWGD PIRLRHLYTS GPHGLSSCFL RIRADGVVDC ARGQSAHSLLEIKAVALRTV AIKGVHSVRY LCMGADGKMQ GLLQYSEEDC AFEEEIRPDG YNVYRSEKHR LPVSLSSAKQ RQLYKNRGFL PLSHFLPMLP MVPEEPEDLR GHLESDMFSS PLETDSMDPF GLVTGLEAVR SPSFEK.

Storage Instruction

Lyophilized FGF-19 Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fibroblast Growth Factor-19 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

Add deionized water to a working concentration approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture.

References

Not Available
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FGF19, His
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