FGF19, HEK

Alternative Names: fibroblast growth factor 19, FGF19,

fibroblast growth factor 19.

FGF-19 is a member of the FGF family that interacts with various FGFR receptors. It suppresses bile acid biosynthesis by downregulating CYP7A1 expression. FGF-19 also stimulates glucose uptake in adipocytes and is a high affinity ligand for FGFR4, dependent on heparin.

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  • Sku: PSB-cyt-1180-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Fibroblast Growth Factor-19, HEK is a member of the fibroblast growth factor (FGF) family, specifically FGF-19. With a molecular weight of approximately 21 kDa, this protein plays a role in various cellular processes such as cell growth, differentiation, and proliferation. Produced in human embryonic kidney (HEK) cells using recombinant DNA technology, Recombinant Human Fibroblast Growth Factor-19 is commonly used in research and therapeutic applications for its ability to regulate metabolic pathways and promote tissue regeneration.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 95.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation FGF19 protein (0.5mg/ml) contains 20mM Tris-HCl(pH8.0), 20% glycerol and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

DGSHMRPLAF SDAGPHVHYG WGDPIRLRHL YTSGPHGLSS CFLRIRADGV VDCARGQSAH SLLEIKAVAL RTVAIKGVHS VRYLCMGADG KMQGLLQYSE EDCAFEEEIR PDGYNVYRSE KHRLPVSLSS AKQRQLYKNR GFLPLSHFLP MLPMVPEEPE DLRGHLESDM FSSPLETDSM DPFGLVTGLE AVRSPSFEKH HHHHH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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FGF19, HEK

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