FGF19

Alternative Names: Fibroblast growth factor 19, FGF19, FGF-19

The FGFs are a group of small secreted peptides that stimulate fibroblast proliferation through specific receptors. Different FGF receptors have varying effects on cellular activity, with evidence suggesting they play a role in glucose and lipid regulation. FGF-19 has been shown to resist obesity and improve insulin and lipid profiles in rodents, while FGF-21 activates glucose uptake in adipocytes and lowers blood glucose and triglyceride levels in diabetic animals. Further research is needed to fully understand the biological functions of FGF-21.

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  • Sku: PSB-cyt-700-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Fibroblast Growth Factor-19 (FGF-19) is a member of the fibroblast growth factor family, which plays a key role in cell growth, proliferation, and differentiation. FGF-19 is a protein with a molecular weight of approximately 25 kDa. It is involved in various biological processes, including tissue repair, wound healing, and metabolic regulation. Recombinant Human FGF-19 is commonly used in research and therapeutic applications due to its potent biological activities.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The ED50 as determined by the dose-dependent stimulation of the proliferation of balb/c 3T3 cells is 100-150ng/ml. The ED50 as determined by the dose-dependent stimulation of the proliferation of balb/c 3T3 cells is 100-150ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Filtered (0.2µm) and lyophilized from 1mg/ml in 1xPBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK.

Storage Instruction

Lyophilized FGF-19 Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fibroblast Growth Factor-19 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized FGF-19 in sterile 1X PBS ;not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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FGF19
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