FGF12, His

Alternative Names: Fibroblast growth factor 12, FGF-12, FGF12, FGF12B, Fibroblast growth factor homologous factor 1, FHF-1, FHF1, Myocyte-activating factor.

FGF12, a member of the Fibroblast Growth Factor (FGF) family, plays a critical role in various biological processes such as embryonic development, cell growth, tissue repair, and nervous system development. Despite lacking a typical N-terminal signal sequence, FGF12 contains basic residues that facilitate its nuclear localization when transfected into mammalian cells. FGF12 interacts with IB2 and voltage gated sodium channels, contributing to intracellular signaling and ion exchange.

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  • Sku: PSB-cyt-620-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Fibroblast Growth Factor 12, His Tag is a protein belonging to the fibroblast growth factor family. This protein plays a role in cell growth, proliferation, and differentiation. With a molecular weight of approximately 22 kDa, Recombinant Human Fibroblast Growth Factor 12, His Tag is commonly used in research and biotechnology applications for its ability to stimulate cell growth and promote tissue regeneration.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The FGF-12 solution (1mg/ml) contains 20mM Tris pH-7.5, 1mM DTT, 2mM EDTA and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MSSHHHHHH SSGLVPRGSH MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE YLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKP IEVCMYREQS LHEIGEKQGR RKSSGTPTM NGGKVVNQDS T.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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FGF12, His

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