FGF1 155 a.a.

Alternative Names: ECGF, ECGFA, ECGF-beta, FGF-a, FGF1, FGFIBP, FIBP, FIBP-1, HBGF-1, GLIO703.

Acidic fibroblast growth factor, a member of the FGF family, plays a role in various biological processes such as cell growth, tissue repair, and tumor growth. It functions as a stimulator of endothelial cell migration and proliferation, as well as an angiogenic factor. FGF1 is involved in organogenesis and has multiple isoforms due to alternative splicing. It is known to be a potent mitogen for different types of cells both in vitro and in vivo. Differences exist in the tissue distribution and concentration of FGF1 compared to other growth factors.

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  • Sku: PSB-cyt-1112-10µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Fibroblast Growth Factor-acidic (155 a.a.) is a member of the fibroblast growth factor family, known for its role in cell proliferation and differentiation. This protein weighs approximately 17 kDa and plays a key role in wound healing and tissue repair. Its recombinant form is commonly used in research and therapeutic applications due to its ability to stimulate cell growth and migration.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0 % by SDS-PAGE
Activity
 The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is < than 0.5 ng/ml, corresponding to a specific activity of > 2.0 ×106 IU/mg in the presence of 10µg/ml Heparin.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 17.3 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4, with 0.5mM DTT, 2mM EDTA, and 5 % Trehalose.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AEGEITTFTA LTEKFNLPPG NYKKPKLLYC SNGGHFLRIL PDGTVDGTRD RSDQHIQLQL SAESVGEVYI KSTETGQYLA MDTDGLLYGS QTPNEECLFL ERLEENHYNT YISKKHAEKN WFVGLKKNGS CKRGPRTHYG QKAILFLPLP VSSD.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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FGF1 155 a.a.
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