FGF1

Alternative Names: ECGF, ECGFA, ECGF-beta, FGF1, FGF-a, FGFIBP, FIBP, FIBP-1, HBGF-1, GLIO703

Acidic fibroblast growth factor, a member of the FGF family, plays a role in various biological processes such as cell growth and tissue repair. It is involved in endothelial cell migration and proliferation, acting as an angiogenic factor. This protein is a mitogen for different cell types, suggesting its involvement in organogenesis. Different isoforms have been identified, with varying tissue distribution and concentration, highlighting the diverse functions of this growth factor.

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  • Sku: PSB-cyt-264-10µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Fibroblast Growth Factor-acidic, also known as FGF-1, is a member of the fibroblast growth factor family. It plays a crucial role in cell proliferation, differentiation, and survival. FGF-1 is a low molecular weight protein, with a molecular weight of approximately 17 kDa. This growth factor is commonly used in research and therapeutic applications due to its ability to stimulate cell growth and tissue repair.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The ED50, calculated by the dose-dependant proliferation of mouse BALB/c 3T3 cells is <0.5 ng/ml, corresponding to a specific activity of > 2,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 15.8 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The protein was lyophilized from a concentrated (1mg/ml) sterile solution containing PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D.

Storage Instruction

Lyophilized Fibroblast Growth Factor-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-a should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-acidic in sterile 18MΩ-cm H2O at 4 degrees Celsius at a concentration of 0.1mg-0.25mg per 1ml. Allow sample to sit for 5 min. at 4 degrees, spin to remove precipitant.

References

Not Available
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FGF1
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