Ferritin Light

Alternative Names: Ferritin light chain, Ferritin, FTL, MGC71996.

Ferritin is a large iron-storage protein composed of two subunit types, light and heavy ferritin polypeptides. It is found in various cells and has different proportions in different tissues. Ferritin is made up of 24 self-assembled polypeptide subunits and is capable of removing iron from solution in the presence of oxygen. The light ferritin protein is the main intracellular iron storage protein and its composition affects iron uptake and release rates in different tissues. Ferritin's main function is to store iron in a soluble and safe form. Defects in the light chain ferritin gene are associated with neurodegenerative diseases and hyperferritanemia-cataract syndrome. Overall, ferritin plays a crucial role in maintaining iron balance by storing iron in a soluble, non-toxic form that is easily accessible.

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  • Sku: PSB-pro-650-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Ferritin Light Chain is a protein that belongs to the ferritin family, which plays a crucial role in iron storage and homeostasis. With a molecular weight of approximately 19 kDa, this protein is involved in the formation of ferritin, a hollow spherical shell that encapsulates and stores iron ions in a safe and bioavailable form. Recombinant Human Ferritin Light Chain is widely utilized in various research applications, including studies related to iron metabolism, drug delivery systems, and diagnostic assays. Its precise structural and functional characteristics make it a valuable tool in understanding iron-related disorders and developing therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The protein solution (1mg/ml) contains 20mM Tris-HCl pH-7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLFERL TLKHD.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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Ferritin Light

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