• Home
  • Ferritin Heavy

Ferritin Heavy

Alternative Names: Ferritin heavy chain, FTH1, FHC, FTH, PLIF, FTHL6, Cell proliferation-inducing gene 15 protein, PIG15, MGC104426.

Ferritin is a large iron-storage protein found in various cells. It consists of two subunit types, light and heavy ferritin, which assemble in different proportions depending on the tissue. Ferritin is composed of 24 polypeptide subunits and has the ability to remove Fe (II) from solution in the presence of oxygen. The light polypeptide protein is the main intracellular iron storage protein in both prokaryotes and eukaryotes. Different compositions of ferritin subunits affect the rates of iron uptake and release in different tissues. One important function of ferritin is to store iron in a soluble and nontoxic form. Mutations in the light chain ferritin gene are associated with neurodegenerative diseases and hyper ferrit anemia-cataract syndrome. Overall, ferritin plays a crucial role in maintaining iron balance by storing iron in a safe and accessible form.

  •
  • Sku: PSB-pro-658-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Ferritin Heavy Chain is a protein that belongs to the ferritin family, which plays a key role in iron storage and homeostasis. With a molecular weight of approximately 21 kDa, this protein is involved in the encapsulation and storage of iron within its hollow spherical structure. Recombinant Human Ferritin Heavy Chain serves as a vital component in various biological processes, including iron metabolism and detoxification, making it a significant target for scientific research and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The FTH1 protein solution contains 20mM Tris-HCl pH-7.5, 1mM DTT and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

Ferritin Heavy
SUBHEADING

Recently viewed products