FCMR

Alternative Names: Fas apoptotic inhibitory molecule 3, FAIM3, IgM Fc fragment receptor, Regulator of Fas-induced apoptosis Toso, TOSO.

FCMR, also known as fas apoptotic inhibitory molecule 3, plays a role in immune system processes. It protects cells from apoptosis caused by FADD, FAS, and TNF alpha proteins, without overexpressing apoptosis inhibitors like BCLXL and BCL2. Instead of blocking apoptotic signals downstream, FCMR activates an inhibitory pathway to prevent CASP8 activation.

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  • Sku: PSB-pro-2579-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

The Recombinant Human Fc Fragment Of IgM Receptor is a protein molecule that plays a significant role in immune responses. Belonging to the immunoglobulin superfamily, this receptor is involved in the recognition and binding of IgM antibodies, thereby facilitating various immune functions. With a molecular weight of [insert weight], this receptor acts as a mediator between the innate and adaptive immune systems, contributing to the regulation of immune cell activation and antibody production. Its precise functions and interactions make it a valuable target for research and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
27.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation FCMR filtered (0.4 µm) and lyophilized from 0.5mg/ml in 50mM acetate buffer, pH 4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MKHHHHHHAS RILPEVKVEG ELGGSVTIKC PLPEMHVRIY LCREMAGSGT CGTVVSTTNF IKAEYKGRVT LKQYPRKNLF LVEVTQLTES DSGVYACGAG MNTDRGKTQK VTLNVHSEYE PSWEEQPMPE TPKWFHLPYL FQMPAYASSS KFVTRVTTPA QRGKVPPVHH SSPTTQITHR PRVSRASSVA GDKPRTFLPS TTASKISALE GLLKPQTPSY NHHTRLHRQR ALDYGSQSGR EGQ.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add 0.1M acetate buffer, pH 4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. In higher concentrations the solubility of this antigen is limited.

References

Not Available

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FCMR

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