FCGRT

Alternative Names: IgG receptor FcRn large subunit p51, FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor, Fcgrt, Fcrn

The Recombinant Human Fc Fragment of IgG Receptor and Transporter is a protein that belongs to the immunoglobulin superfamily. With a molecular weight of [insert weight], it plays a significant role in the immune system by mediating the binding and transport of immunoglobulin G (IgG) molecules. This receptor and transporter protein is involved in various immune processes, including antibody-dependent cellular cytotoxicity (ADCC) and antibody transport across epithelial barriers. Its precise functions make it a valuable tool in research and therapeutic applications related to immunology and antibody-based therapies.

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  • Sku: PSB-pro-2806-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

The Recombinant Human Fc Fragment of IgG Receptor and Transporter is a protein that belongs to the immunoglobulin superfamily. With a molecular weight of [insert weight], it plays a significant role in the immune system by mediating the binding and transport of immunoglobulin G (IgG) molecules. This receptor and transporter protein is involved in various immune processes, including antibody-dependent cellular cytotoxicity (ADCC) and antibody transport across epithelial barriers. Its precise functions make it a valuable tool in research and therapeutic applications related to immunology and antibody-based therapies.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 95.0 by SDS-PAGE
Activity
Measured by its binding ability in a functional ELISA with Human IgG1 Fc.
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
31.1 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The FCGRT solution (0.25mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

FCGRT AESHLSLLYH LTAVSSPAPG TPAFWVSGWL GPQQYLSYNS LRGEAEPCGA WVWENQVSWY WEKETTDLRI KEKLFLEAFK ALGGKGPYTL QGLLGCELGP DNTSVPTAKF ALNGEEFMNF DLKQGTWGGD WPEALAISQR WQQQDKAANK ELTFLLFSCP HRLREHLERG RGNLEWKEPP SMRLKARPSS PGFSVLTCSA FSFYPPELQL RFLRNGLAAG TGQGDFGPNS DGSFHASSSL TVKSGDEHHY CCIVQHAGLA QPLRVELESP AKSSHHHHHH. B2M IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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FCGRT

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