FCER1A , HEK

Alternative Names: FCERIA, FCERA, FcERI, FCER1A, FCE1A, Fc epsilon receptor Ia, Fcepsilon RI-alpha, Fc epsilon RI alpha chain, High affinity immunoglobulin epsilon receptor subunit alpha isoform1, IgE Fc receptor subunit alpha

Recombinant Human Fc-Epsilon RI-Alpha, HEK, is a protein belonging to the family of Fc receptors. With a molecular weight of approximately X kDa, this protein plays a significant role in immune responses. It functions as a high-affinity receptor for the Fc region of immunoglobulin E (IgE), facilitating the binding of IgE antibodies to mast cells and basophils. This interaction triggers a cascade of signaling events, ultimately leading to the release of inflammatory mediators. The Recombinant Human Fc-Epsilon RI-Alpha, HEK, protein is widely utilized in research studies to investigate the mechanisms underlying allergic reactions and develop potential therapeutic interventions.

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  • Sku: PSB-pro-2779-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Fc-Epsilon RI-Alpha, HEK, is a protein belonging to the family of Fc receptors. With a molecular weight of approximately X kDa, this protein plays a significant role in immune responses. It functions as a high-affinity receptor for the Fc region of immunoglobulin E (IgE), facilitating the binding of IgE antibodies to mast cells and basophils. This interaction triggers a cascade of signaling events, ultimately leading to the release of inflammatory mediators. The Recombinant Human Fc-Epsilon RI-Alpha, HEK, protein is widely utilized in research studies to investigate the mechanisms underlying allergic reactions and develop potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 90 by SDS-PAGE
Activity
The ED50 range ≤ 0.01 ug/ml and is measured by its binding ability in a functional ELISA with Human IgE.
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
21.8 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation FCER1A protein solution (1mg/ml) containing 10% Glycerol and Phosphate-Buffered Saline (pH 7.4).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

VPQKPKVSLN PPWNRIFKGE NVTLTCNGNN FFEVSSTKWF HNGSLSEETN SSLNIVNAKF EDSGEYKCQH QQVNESEPVY LEVFSDWLLL QASAEVVMEG QPLFLRCHGW RNWDVYKVIY YKDGEALKYW YENHNISITN ATVEDSGTYY CTGKVWQLDY ESEPLNITVI KAPREKYWLQ HHHHHH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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FCER1A , HEK

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