FAS His

Alternative Names: Tumor necrosis factor receptor superfamily member 6, CD95, CD-95, FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, CD95 antigen, FAS, APT1, FAS1, TNFRSF6, APO-1, FASTM, ALPS1A.

FAS/CD95 is a 36kDa type I receptor in the NF/NGF receptor superfamily that induces cell apoptosis when interacting with CD95L. Tumor cells may down-regulate CD95 expression as a way to resist killing by immune cells. CD95 is found on activated T and B lymphocytes as well as other non-transformed cells.

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  • Sku: PSB-pro-594-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human sFAS Receptor, His Tag is a protein belonging to the tumor necrosis factor receptor superfamily. It is commonly used in research and drug development due to its ability to bind to FAS ligand and regulate apoptosis. This protein has a molecular weight of approximately 18-20 kDa and is often utilized in studies related to cell death and survival pathways. Its His Tag allows for easy purification and detection in laboratory settings.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation 10mM Sodium Phosphate, pH 8.0.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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FAS His

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