FABP2 His

Alternative Names: Fatty acid-binding protein 2, IFABP, I-FABP, FABPI, FABP-2, Fatty acid-binding protein intestinal, FABP2, MGC133132.

The FABP multigene family consists of nearly 20 known members. These members are categorized into three types: hepatic, intestinal, and cardiac. They are small proteins, weighing approximately 14-15 kDa, and play a role in the uptake, intracellular metabolism, and/or transport of long-chain fatty acids. FABPs are also involved in regulating cell growth and proliferation. The gene for intestinal FABP, known as FABP2, has a polymorphism at codon 54 that results in the presence of either an alanine-encoding allele or a threonine-encoding allele. The presence of the threonine-encoding allele is associated with increased fat oxidation and insulin resistance. In patients with ulcerative colitis, high levels of FABP2 in the serum indicate the presence of ileitis. FABP2 is involved in the synthesis of triglyceride-rich lipoproteins. It binds to saturated long-chain fatty acids with a high affinity, but has a lower affinity for unsaturated long-chain fatty acids. By functioning as a lipid sensor, FABP2 helps regulate energy homeostasis.

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  • Sku: PSB-pro-669-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Product Details

Product Description

Recombinant Human Fatty Acid Binding Protein-2, His Tag, is a protein belonging to the fatty acid binding protein (FABP) family. This protein, with a molecular weight of approximately [insert weight], plays a significant role in lipid metabolism and transport. It exhibits a high affinity for fatty acids and is involved in their intracellular transportation, facilitating their utilization and storage. The His tag, a short amino acid sequence, allows for easy purification and detection of the protein. Overall, Recombinant Human Fatty Acid Binding Protein-2, His Tag, serves as a valuable tool in studying and understanding the intricate mechanisms underlying fatty acid metabolism.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation FABP2 His-Tag is supplied in 20mM Tris-HCl pH 8 and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSAFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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FABP2 His
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