FABP2

Alternative Names: IFABP, I-FABP, FABPI, FABP-2, Fatty acid-binding protein 2, Fatty acid-binding protein intestinal, FABP2, MGC133132.

The FABP multigene family consists of around 20 members, which can be divided into three types: hepatic, intestinal, and cardiac. These types of FABPs are small proteins that weigh approximately 14-15 kDa. They play a role in the uptake, intracellular metabolism, and/or transportation of long-chain fatty acids. FABPs are also involved in regulating cell growth and proliferation. The intestinal FABP gene, known as FABP2, has a variation at codon 54 that results in either an alanine-encoding allele or a threonine-encoding allele. The threonine variant (Thr-54) is associated with increased fat oxidation and resistance. Ulcerative colitis patients with high serum levels of FABP2 often have ileitis. FABP2 also plays a role in the synthesis of triglyceride-rich lipoproteins. It has a strong affinity for saturated long-chain fatty acids, but a weaker affinity for unsaturated long-chain fatty acids. Overall, FABP2 helps maintain energy homeostasis by acting as a lipid sensor.

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  • Sku: PSB-pro-1579-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Fatty Acid Binding Protein-2 (FABP2) is a protein that belongs to the fatty acid binding protein family. It plays a significant role in the intracellular transport of fatty acids and their metabolism. FABP2 has a molecular weight of approximately 15 kDa and is abundantly expressed in the small intestine. This protein is involved in the absorption and utilization of dietary fatty acids, making it a crucial player in lipid metabolism. Understanding the function and structure of FABP2 can provide valuable insights into various metabolic disorders and aid in the development of therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 15.1 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation FABP2 was lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AFDSTWKVDR SENYDKFMEK MGVNIVKRKL AAHDNLKLTI TQEGNKFTVK ESSAFRNIEV VFELGVTFNY NLADGTELRG TWSLEGNKLI GKFKRTDNGN ELNTVREIIG DELVQTYVYE GVEAKRIFKK D.

Storage Instruction

Lyophilized FABP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FABP2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Interleukin FABP2 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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FABP2
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