EXOSC7

Alternative Names: Exosome Component 7, RRP42, Ribosomal RNA-Processing Protein 42, Exosome Complex Exonuclease RRP42, Exosome Complex Component RRP42, KIAA0116, HRrp42p, EAP1, P8.

EXOSC7 is a member of the RNase PH family and a component of the RNA exosome complex. It is involved in multiple pathways, including transfer to a nascent protein, Unfolded Protein Response, and Biosynthesis of the N-glycan precursor. A closely related gene is EXOSC9.

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  • Sku: PSB-pro-2144-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Exosome Component 7, also known as EXOSC7, is a vital protein involved in the formation and function of exosomes. Exosomes are small extracellular vesicles secreted by various cell types and play a significant role in intercellular communication. EXOSC7 belongs to the exosome complex, a multi-protein complex responsible for RNA degradation and processing. With a molecular weight of approximately X kDa, EXOSC7 contributes to the stability and integrity of the exosome complex, facilitating its role in RNA metabolism and cellular homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
34.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation EXOSC7 protein solution (0.5mg/ml) containing 20mM Tris-HCl(pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMASVTLS EAEKVYIVHG VQEDLRVDGR GCEDYRCVEV ETDVVSNTSG SARVKLGHTD ILVGVKAEMG TPKLEKPNEG YLEFFVDCSA SATPEFEGRG GDDLGTEIAN TLYRIFNNKS SVDLKTLCIS PREHCWVLYV DVLLLECGGN LFDAISIAVK AALFNTRIPR VRVLEDEEGS KDIELSDDPY DCIRLSVENV PCIVTLCKIG YRHVVDATLQ EEACSLASLL VSVTSKGVVT CMRKVGKGSL DPESIFEMME TGKRVGKVLH ASLQSVVHKE ESLGPKRQKV GFLG

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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EXOSC7

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