Exodus-2

Alternative Names: Small inducible cytokine A21, SCYA21, CCL21, chemokine (C-C motif) ligand 21, CKb9, Beta chemokine exodus-2, 6Ckine, ECL, Secondary lymphoid-tissue chemokine, SLC, TCA4, MGC34555.

CCL21, a member of the CC chemokine family, is also known as 6Ckine, exodus-2, and SLC. It is primarily found in lymph nodes and attracts lymphocytes. CCL21 acts by binding to the CCR7 receptor on cell surfaces, and its gene is located on human chromosome 9.

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  • Sku: PSB-chm-332-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Exodus-2 (CCL21) is a chemokine protein that belongs to the CC chemokine family. It plays a role in immune cell trafficking and inflammation by binding to its receptor, CCR7. This protein has a molecular weight of approximately 12.5 kDa. Recombinant Human Exodus-2 (CCL21) is commonly used in research studies to investigate its role in various immune responses and inflammatory diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
Determined by its ability to chemoattract human total lymphocyte population using a concentration range of 10-100ng/ml. Determined by its ability to chemoattract human total lymphocyte population using a concentration range of 10-100ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 20mM Phosphate Buffer, pH 7.4 and 150mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P.

Storage Instruction

Lyophilized Exodus-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Exodus-2

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