Exenatide

Alternative Names: Exendin-4

Exenatide, a peptide derived from gila monster saliva, acts similarly to GLP-1 incretin to improve insulin release, suppress glucagon release, regulate gastric emptying, and reduce appetite, ultimately lowering blood glucose levels. It self-regulates by lowering blood sugar only when levels are high and does not continue to lower levels when they return to normal, distinguishing it from sulfonylureas or insulins.

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  • Sku: PSB-hor-246-1mg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Exenatide is a medication used to treat type 2 diabetes by helping to control blood sugar levels. It belongs to the glucagon-like peptide-1 (GLP-1) receptor agonist family, which works by mimicking the effects of the hormone GLP-1. Exenatide has a molecular weight of approximately 4184.72 g/mol and is administered through injection to help improve glycemic control in patients with diabetes. Its mechanism of action involves stimulating insulin secretion and inhibiting glucagon release, ultimately leading to better blood sugar regulation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Contact for Details
Purity 99.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The Exenatide peptide was lyophilized from a concentrated solution with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2.

Storage Instruction

Lyophilized Exenatide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Exenatide should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Exenatide in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Exenatide

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