eVEGF

Alternative Names: VEGF-A, VPF, glioma-derived endothelial cell mitogen, VEGF-A, VPF, glioma-derived endothelial cell mitogen.

Vascular endothelial growth factor (VEGF) is a key signaling protein involved in vasculogenesis and angiogenesis. Its main effects are on vascular endothelial cells, but it also affects other cell types such as monocytes, neurons, cancer cells, and kidney epithelial cells. VEGF promotes cell growth, migration, and inhibits cell death. It also increases vascular permeability and induces the formation of new blood vessels. Elevated VEGF levels are associated with POEMS syndrome and diabetic retinopathy.

  •
  • Sku: PSB-cyt-1200-10µg
  • Vendor: ProSpec-Tany
$130.00 USD
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Title
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Equine Vascular Endothelial Growth Factor (VEGF) is a member of the VEGF family, which plays a key role in angiogenesis and vasculogenesis. This protein is responsible for stimulating the growth of new blood vessels from pre-existing vessels. Recombinant Equine VEGF has a molecular weight of approximately 40 kDa and is commonly used in research and therapeutic applications related to vascular development and regeneration in horses.

Current Lead Time

7-14 Days

Product Specifications

Species
 Horse
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The ED50 as determined by HUVEC Proliferation is ≤ 10 ng/mL, corresponding to a specific activity of ≥ 1.0 x 10^5 units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM Sodium Phosphate, pH 7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MAPMAEGEHK THEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TAEFNITMQI MRIKPHQSQH IGEMSFLQHS KCECRPKKDK ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

Storage Instruction

Lyophilized VEGF although stable at room temperature for 3 weeks, should be stored desiccated below -18° C. Upon reconstitution VEGF Human should be stored at 4° C between 2-7 days and for future use below -18° C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized VEGF in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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eVEGF
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