ERP27

Alternative Names: ER protein 27, ERp27, ERP27, PDIA8, C12orf46, FLJ32115, Endoplasmic reticulum resident protein 27

Endoplasmic reticulum protein 27kDa (ERP27) is a widely expressed protein found in the ER. It has various functions such as acting as a protease, protein disulfide isomerase, thiol-disulfide oxidase, or phospholipase. Unlike other members of the protein disulfide isomerase family, ERP27 does not possess a CXXC active site motif, making it inactive in catalyzing redox reactions.

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  • Sku: PSB-pro-046-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Endoplasmic Reticulum Protein 27 (ERp27) is a protein that plays a significant role in the endoplasmic reticulum (ER) of eukaryotic cells. Belonging to the protein disulfide isomerase (PDI) family, ERp27 is involved in protein folding and assembly, as well as the maintenance of redox homeostasis within the ER. With a molecular weight of approximately X kDa, ERp27 aids in the proper formation of disulfide bonds, ensuring the structural integrity and functionality of various proteins within the ER. Its precise functions and mechanisms are still under investigation, making ERp27 an intriguing subject for further scientific exploration.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ERP27 solution (1mg/ml) contains 20mM Tris buffer (pH 8.0), 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MEVEKSSDGP GAAQEPTWLT DVPAAMEFIA ATEVAVIGFF QDLEIPAVPI LHSMVQKFPG VSFGISTDSE VLTHYNITGN TICLFRLVDN EQLNLEDEDI ESIDATKLSR FIEINSLHMV TEYNPVTVIG LFNSVIQIHL LLIMNKASPE YEENMHRYQK AAKLFQGKIL FILVDSGMKE NGKVISFFKL KESQLPALAI YQTLDDEWDT LPTAEVSVEH VQNFCDGFLS GKLLKENRES EGKTPKVEL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ERP27

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