EREG, His

Alternative Names: Proepiregulin, Epiregulin, ERP, ER

Epiregulin, a member of the EGF family, acts as a ligand for EGFR and most members of the ERBB family of tyrosine-kinase receptors. It is primarily found in the placenta, peripheral blood leukocytes, and specific carcinomas. Epiregulin promotes the growth of various cell types while inhibiting the growth of certain tumor-derived epithelial cell lines. In humans, Epiregulin is first produced as a glycosylated transmembrane precursor protein, then cleaved to form a smaller mature secreted sequence.

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  • Sku: PSB-cyt-859-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Epiregulin, His Tag is a protein belonging to the epidermal growth factor (EGF) family. It is a signaling molecule involved in cell growth, proliferation, and differentiation. This protein has a molecular weight of approximately 6.5 kDa. Recombinant Human Epiregulin, His Tag is commonly used in research and biotechnology applications for its role in regulating cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation EREG protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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EREG, His

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