EPGN

Alternative Names: EPG, Epigen, PRO9904, ALGV3072, FLJ75542, EPGN, Epithelial mitogen.

EPGN is an EGF-related growth factor that acts through the ErbB receptor-1. It is produced in various tissues and has a mitogenic effect on fibroblasts and epithelial cells. Human EPGN is initially synthesized as a glycosylated transmembrane precursor protein, which is later cleaved to produce a mature soluble form.

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  • Sku: PSB-cyt-601-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Epigen is a member of the epigen family, a group of proteins involved in regulating gene expression. With a molecular weight of approximately 25 kDa, this protein plays a key role in modulating chromatin structure and influencing transcriptional activity. Recombinant Human Epigen is commonly used in research settings to study epigenetic mechanisms and their impact on cellular function.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 98.0 % by SDS-PAGE
Activity
Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300ng/ml, corresponding to a specific activity of 3,334-6,667IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation EPGN was lyophilized from 20mM PBS buffer pH-7.4 containing 130mM sodium chloride.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

Storage Instruction

Lyophilized Epigen although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution EPGN should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Epigen in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. ;

References

Not Available

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EPGN

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