Eotaxin, His

Alternative Names: Small inducible cytokine A11, SCYA11, CCL11, Eosinophil chemotactic protein, chemokine (C-C motif) ligand 11, MGC22554.

CCL11, also known as eotaxin, is a small cytokine in the CC chemokine family that attracts eosinophils and is involved in allergic responses. Its effects are carried out through binding to chemokine receptors such as CCR2, CCR3, and CCR5. The human gene for CCL11, located on chromosome 17, is comprised of three exons.

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  • Sku: PSB-chm-344-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Eotaxin (CCL11), His Tag is a protein belonging to the chemokine family. It plays a role in immune response and inflammation by attracting eosinophils to sites of infection or injury. This recombinant protein has a molecular weight of approximately 8.8 kDa and is commonly used in research and drug development for its ability to modulate immune cell trafficking. The His Tag allows for easy purification and detection of the protein in various assays.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation Eotaxin-His is supplied liquid In Phosphate Buffered Saline pH7.4 containing 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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Eotaxin, His

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