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ENA 78 (8-78 a.a.)

Alternative Names: Small inducible cytokine B5, SCYB5, CXCL5, chemokine (C-X-C motif) ligand 5, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, ENA-78(1-78)

CXCL5 is a small cytokine in the CXC chemokine family, also known as ENA-78. It is produced in response to inflammatory cytokines and expression has been seen in eosinophils. Its effects include stimulating neutrophil chemotaxis and possessing angiogenic properties by interacting with the CXCR2 receptor. The gene for CXCL5 is found on human chromosome 4.

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  • Sku: PSB-chm-265-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Epithelial Neutrophil-Activating Protein 78 (CXCL5), 8-78 a.a. is a member of the CXC chemokine family, known for its role in immune response regulation. With a molecular weight of approximately 8-78 amino acids, this protein functions as a chemoattractant for neutrophils, promoting their activation and migration to sites of inflammation. Its ability to modulate the immune system makes it a valuable tool for research in the fields of immunology and inflammation.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 The biological activity was determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml. The biological activity was determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N.

Storage Instruction

Lyophilized ENA78 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized ENA-78 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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ENA 78 (8-78 a.a.)
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