ELP5

Alternative Names: C17orf81, DERP6, HSPC002, MST071, MSTP071, Dermal papilla-derived protein 6, S-phase 2 protein, ELP5.

ELP5 is a subunit of the ELP5 family. It functions as a subunit of the RNA polymerase II elongator complex, which is involved in transcriptional elongation. The elongator complex is also a histone acetyltransferase component of the RNA polymerase II holoenzyme. It plays a role in chromatin remodeling and is involved in the acetylation of histones H3 and possibly H4. ELP5 is widely expressed in various tissues such as the heart, brain, liver, skeletal muscle, and testis. Additionally, it is involved in cell migration.

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  • Sku: PSB-pro-1660-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Elongator Acetyltransferase Complex Subunit 5, also known as ELP5, is a protein that plays a vital role in the Elongator complex, a highly conserved protein complex found in eukaryotes. ELP5 belongs to the family of acetyltransferases and is involved in the acetylation of elongator tRNA during transcriptional elongation. With a molecular weight of approximately X kDa, ELP5 contributes to the proper functioning of the Elongator complex, which is implicated in various cellular processes, including transcriptional regulation and tRNA modification.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
37.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation ELP5 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMTPSEGA RAGTGRELEM LDSLLALGGL VLLRDSVEWE GRSLLKALVK KSALCGEQVH ILGCEVSEEE FREGFDSDIN NRLVYHDFFR DPLNWSKTEE AFPGGPLGAL RAMCKRTDPV PVTIALDSLS WLLLRLPCTT LCQVLHAVSH QDSCPGDSSS VGKVSVLGLL HEELHGPGPV GALSSLAQTE VTLGGTMGQA SAHILCRRPR QRPTDQTQWF SILPDFSLDL QEGPSVESQP YSDPHIPPVD PTTHLTFNLH LSKKEREARD SLILPFQFSS EKQQALLRPR PGQATSHIFY EPDAYDDLDQ EDPDDDLDI.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ELP5

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