eIL1B

Alternative Names: Catabolin, Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta, Lymphocyte-activating factor (LAF)

Interleukin-1b, produced by activated macrophages, promotes thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. These proteins are also involved in the inflammatory response as endogenous pyrogens, stimulating the release of prostaglandin and collagenase from synovial cells.

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  • Sku: PSB-cyt-411-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Equine Interleukin-1 beta is a protein belonging to the interleukin-1 family, known for its role in mediating inflammatory responses in horses. With a molecular weight of approximately 17 kDa, this cytokine plays a key role in regulating immune and inflammatory processes in equine species. Recombinant Equine Interleukin-1 beta is commonly used in research and therapeutic applications to study and modulate immune responses in horses.

Current Lead Time

7-14 Days

Product Specifications

Species
 Horse
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 20 pg/ml, corresponding to a specific activity of > 5.0 × 107 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 17.3 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The IL 1 beta was lyophilized from a 0.2µm filtered concentrated solution in PBS pH 7.4, containing 0.1 % Tween-80.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AAMHSVNCRL RDIYHKSLVL SGACELQAVH LNGENTNQQV VFCMSFVQGE EETDKIPVAL GLKEKNLYLS CGMKDGKPTL QLETVDPNTY PKRKMEKRFV FNKMEIKGNV EFESAMYPNW YISTSQAEKS PVFLGNTRGG RDITDFIMEI TSA

Storage Instruction

Lyophilized IL 1 beta although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL 1 beta should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized IL 1 beta in sterile distilled H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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eIL1B
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